Lets, say DataGridView1 is your DataGridView.
Then to Delete a Single Row write following code:
DataGridView1.Rows.Remove(DataGridView1.CurrentRow)To Delete Multiple Rows call following sub on Event Handler or Button Click:-Private Sub ClearDataGrid()
For Each row As DataGridViewRow In DataGridView1.Rows
DataGridView1.Rows.Remove(row)
Next
End SubOR you can even simply do,DataGridView1.Rows.Clear()