asp.net c#..How to create a website in tamil???

Simple change UICulture and culture to tamil. like this.. 

<%@ Page UICulture="ta" Culture ="ta-in" %>

 In code behind.. 

            Page.Culture = "ta-in";
            Page.UICulture = "ta";

Refer these..

http://msdn.microsoft.com/en-us/magazine/cc163566.aspx

http://msdn.microsoft.com/en-us/library/system.globalization.cultureinfo.aspx