how can i get path of upload file like (F:\...) in c#

   example : string path =  Server.MapPath("textdoc") + File1.PostedFile.FileName ;

Add into your database table like this.

System.Data.SqlClient.SqlConnection sqlConnection1 =  new System.Data.SqlClient.SqlConnection("YOUR CONNECTION STRING");  
System.Data.SqlClient.SqlCommand cmd = new System.Data.SqlClient.SqlCommand(); 
cmd.CommandType = System.Data.CommandType.Text; 
cmd.CommandText = "INSERT tblimage(ID, ImagePath) VALUES (5, "+path+")"; 
cmd.Connection = sqlConnection1;  
sqlConnection1.Open(); 
cmd.ExecuteNonQuery(); 
sqlConnection1.Close();