sending sms to 1s t column of excel data

Question

Hello everyone,
I have 1 excel sheet in which 2 columns are there>In first column mobile number is inserted and in second column messages are inserted.I want to send sms to all the numbers in excel file with there corresponding messages by uploading the excel file .I uploaded the excel file and getting the 2 columns (i have done this by showing the contents of excelsheet in gridview),but no idea about sending the messages to the numbers by uploading the excel.I have sms gateway.
Plz.help.
Thanks in advance