setup project vdproj problem

hi all,
I have two problem with microsoft setup developer.
First ... after building a setup package it would not be updated by changing project primary output , i rebuilded all projects but setup would be changed. Is there any way to repack it?
Second, in my case I must make a new setup for each build of my project for my customers bcoz of security reason like serial number and hardlock checking parts whick depends on an special number... currenly i use msbuild but it cant build setup project of vdproj!
thanx for ur attention  and sorry for poor english!