Check here : https://www.c-sharpcorner.com/article/how-to-enable-usb-port-in-windows-10/

Step1- Press Windows key + X and select “Device Manager”.
step 2- Expand “Universal Serial Bus controllers”.
Step 3- Right-click on the USB port you want to disable and select “Disable device”. To enable the USB port again, right-click on it and select “Enable device”.