You can have multiple unique keys in a table but can have only one Primary Key. Primary key and unique key does not allow enter duplicate data.Primary key doesn't allow null value.Unique key allows only one null value.
Both primary key and unique enforce uniqueness of the column on which they are defined. But by default primary key creates a clustered index on the column, where are unique creates a nonclustered index by default. Another major difference is that, primary key doesn't allow NULLs, but unique key allows one NULL only.