Need help to insert data when submit button is clicked

Hi friends,

I have created website for my office. It has 3 textboxes, 3 pulldowns.And 1 submit button.So when I click submit button all this data should inserted into database.Let say A,B,C are textboxes, D,E,F are scrolldowns.There is a primary key columns which automatically increments itself when the record is created in the database.My request is how should I write the code in the submit button C# function to create the record in the database.