I find that like any other protocol, Ajax works best in tightly controlled conditions. It wouldn't make much sense for updating nearly the whole page, unless you find that the user experience is improved with an on-page 'loader'. Without going into workarounds, disadvantages will include losing the browser back button / history, issues such as the one your friend mentioned, and also embedded resources and other rich content can suffer as well, and just having an extra layer of complexity to deal with in your app. Don't treat it as magic sauce for your app - make sure every use delivers specific results that benefit your client / audience.