HPE and NVIDIA Launch AI Factory Stack to Drive the Next Industrial Revolution

NVIDIA- HPE

In a major move to fast-track artificial intelligence across global industries, Hewlett-Packard Enterprise (HPE) and NVIDIA have jointly announced a comprehensive suite of new AI factory solutions at HPE Discover 2025 in Las Vegas. The collaboration is set to redefine how enterprises build, scale, and operationalize generative, agentic, and industrial AI, offering a robust foundation for the next wave of digital transformation.

A Unified AI Factory Portfolio: Powering the Future of Enterprise AI

HPE’s expanded NVIDIA AI Computing by HPE portfolio now stands as one of the most extensive in the industry, blending cutting-edge NVIDIA Blackwell GPUs, Spectrum-X Ethernet, BlueField-3 networking, and NVIDIA AI Enterprise software with HPE’s versatile servers, storage, and services. This all-in-one approach eliminates the complexity of assembling disparate AI components, allowing organizations to focus on innovation rather than infrastructure.

Generative, agentic, and physical AI have the potential to transform global productivity and create lasting societal change, but AI is only as good as the infrastructure and data behind it. HPE and NVIDIA are delivering the most comprehensive approach, joining industry-leading AI infrastructure and services to enable organizations to realize their ambitions and deliver sustainable business value.

Antonio Neri, President and CEO of HPE

Key Announcements: Modular Infrastructure and Turnkey AI Platforms

Highlights from the new offerings include:

HPE Private Cloud AI: The next-generation, turnkey AI platform co-engineered with NVIDIA, validated within the NVIDIA Enterprise AI Factory framework. This solution leverages the new HPE ProLiant Compute DL380a Gen12 servers, powered by NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs, delivering a universal platform for a wide spectrum of enterprise and industrial AI use cases. The platform comes pre-integrated with the latest NVIDIA AI Blueprints, including the AI-Q Blueprint for agent creation and workflow automation.

HPE RTX PRO Servers: Now available for order, these servers are designed as a universal data center platform, supporting everything from generative AI to mission-critical industrial workloads.

HPE Compute XD690 with NVIDIA HGX B300: Built on NVIDIA Blackwell Ultra GPUs, this high-performance system is the latest addition to the AI Computing by HPE lineup and is expected to ship in October 2025.

Real-World Impact: Global Partnerships and Industry Use Cases

KDDI Collaboration in Japan: HPE is partnering with KDDI to build an NVIDIA AI infrastructure at the KDDI Osaka Sakai Data Center, utilizing the NVIDIA GB200 NVL72 platform based on the Grace Blackwell architecture. This initiative aims to accelerate AI adoption on a global scale.

AI for Financial Services: HPE will co-test agentic AI, workflows with Accenture’s AI Refinery, running on HPE Private Cloud AI, to streamline sourcing, procurement, and risk analysis in the financial sector.

Expanding the AI Ecosystem: HPE is adding 26 new partners to its “Unleash AI” ecosystem, now offering over 70 packaged AI workloads, from fraud detection and video analytics to sovereign AI and cybersecurity.

Security, Governance, and Customer Experience

Recognizing the importance of robust security and governance in enterprise AI, HPE Private Cloud AI supports air-gapped management, multi-tenancy, and post-quantum cryptography. Customers can also take advantage of a try-before-you-buy program, testing systems in Equinix data centers before committing to a purchase. Additionally, HPE has introduced new AI Acceleration Workshops with NVIDIA to help organizations scale their AI deployments efficiently.

Expert Perspective: Ushering in the Industrial AI Era

We are entering a new industrial era — one defined by the ability to generate intelligence at scale. Together, HPE and NVIDIA are delivering full-stack AI factory infrastructure to drive this transformation, empowering enterprises to harness their data and accelerate innovation with unprecedented speed and precision.

Jensen Huang, founder and CEO of NVIDIA

Conclusion

With these new AI factory solutions, HPE and NVIDIA are setting a new industry benchmark for scalable, secure, and production-ready AI infrastructure. By removing integration barriers and providing a full-stack, modular approach, the partnership is poised to empower organizations worldwide to unlock the full potential of AI, driving innovation, efficiency, and sustainable business value.