Data Grid Validation

You can do it using javascript. call this java script function on click of save button.
say dgrdDayEnd is name of my datagrid. strEmail,strTxtCtrlName name of my textbox.
I have done it for textbox do it for other control in same way.

function btnClick(){
   var obj = window.document.getElementById("dgrdDayEnd")
   var intLoop;
   var intRowCnt; 
   if(window.document.getElementsByName("dgrdDayEnd").length !=0) {
    intRowCnt =  obj.rows.length ;
   for(intLoop=1;intLoop<=intRowCnt;intLoop++){
      if (intLoop < 9){
           var strTxtCtrlName = 'dgrdDayEnd_ctl0' + (intLoop+1) + '_txtDayEnd';
        var strCtrlName = 'dgrdDayEnd_ctl0' + (intLoop+1) + '_chkDayEnd';
        var strEmail = 'dgrdDayEnd_ctl0' + (intLoop+1) + '_txtEmail';
   }
   else{
        var strTxtCtrlName = 'dgrdDayEnd_ctl' + (intLoop+1) + '_txtDayEnd';
        var strCtrlName = 'dgrdDayEnd_ctl' + (intLoop+1) + '_chkDayEnd';
        var strEmail = 'dgrdDayEnd_ctl' + (intLoop+1) + '_txtEmail';
   }
     if (Trim(document.getElementById(strEmail).value) != '' && !isEmail(Trim(document.getElementById(strEmail).value))){
         alert("Enter Valid Email Address ");
         document.getElementById(strEmail).focus();
         document.getElementById(strEmail).select();
            return false;
      }
      if(window.document.getElementById(strTxtCtrlName).disabled == false){
        if(window.document.getElementById(strTxtCtrlName).value == "" ||window.document.getElementById(strTxtCtrlName).value == 0){
             alert("Please enter the No of Copies for DayEnd/No of Copies");
             document.getElementById(strTxtCtrlName).focus();
             document.getElementById(strTxtCtrlName).select();
             return false;
          }
     }
       }
}