Best Way to Load Data to a windows Form

Hello everybody,

We have many applications in VB6 and we want to change them to C# .NET 4.5.
I want to ask you what is the best, not the only the faster one but the
safer and the complete, way to load data to windows form.
Is it the entity framework? Is it datasets and bound controls?
Is it external custom classes with all the business logic and with data readers?
Is it something else?

Please give us road to go across, it will be vey helpfull for us!

Thank you in advance.