Executing an sql script in vb.net

Look into Smo (if it is SQL Server) (adding the correct refs Microsoft.SqlServer.ConnectionInfo and Microsoft.SqlServer.Smo along with something like this)

Imports Microsoft.SqlServer
Imports Microsoft.SqlServer.Management.Smo
Imports System.IO

Public Class Form1

Private Sub Form1_Load(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles MyBase.Load

     Dim sr As StreamReader = New StreamReader("C:\Scripts\somescript.sql")
     Dim somescript As String = sr.ReadToEnd
     Dim SMOServer As Management.Smo.Server = New Management.Smo.Server
     Dim db As Database = SMOServer.Databases("somedatabase")
     db.ExecuteNonQuery(somescript)

End Sub

End Class