how to edit resource value thru coding

Hi,
I want to replace the existing resource value to current value
I was Creating a String is KeyVal & Value is 1.
and execute my application.
I wanna to change the KeyVal Value is 2.
I'll use
--- GET VALUE
string s= Properties.Resources.KeyVal;
-- REPLACE VALUE
Properties.Resources.KeyVal.Replace(1,2);
Its Not Working?
Please help me? how can I change the Value in Runtime thru Coding   
Thanx & Regards,
MsHema