System.IO.File not found Exception

Hi,

 During file copy, I'm giving the absolute file name. But the compiler says file not found always. Is it a problem in my system or any error in my program.

[code]

 Public Sub backupDB()

        Try

            Dim FileToCopy As String

            Dim NewCopy As String

            FileToCopy = "E:\Gyana_projects\Medicine_Stores_Management.accdb"

            NewCopy = String.Format("D:\BackUps\{0:yyyyMMdd}.mdb", Date.Today)

            FileCopy(FileToCopy, NewCopy)

     MsgBox("Backup Successful")

        Catch ex As Exception

            MessageBox.Show(ex.ToString)

        End Try

    End Sub

[/code]

Also I'm Giving the absolute path of the file by Copying it from the address bar

i.e:E:\Gyana_projects

File name is: Medicine_Stores_Management.accdb

Plz help ASAP.

Thanks in advance