User Settings store individual user preferences (like themes or window size), are read/write at runtime, and save to the user's AppData folder.

Application Settings store global configuration (like database connection strings), are read-only at runtime, and reside directly in App.config for all users.

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In WPF (.NET), User Settings and Application Settings Among Us refer to two different scopes of configuration values. The key difference is who they belong to and whether they can change at runtime.

user setting can be read or write at run time and can be save.where as Application setting are read-only , they can be written at design time.