Setup that updates it slf as a new setup is created

I think similar question you have asked in other thread, implement ClickOnce When ever you launch the application it will check for the updates

http://msdn.microsoft.com/en-us/magazine/cc163973.aspx

http://msdn.microsoft.com/en-us/library/t71a733d(VS.80).aspx

in your Setup project, set the "version" to something else.  when you do that, it will tell you that you must get a new product code....just click yes.

set "Check For Newer Version" to false
set "Remove Previous Version" to true

now when you run the setup.exe, it will uninstall the other version, then install the new version.