app development assistance ?

Here's my attempt at that.

You need to use panels rather than group boxes here if that in fact is what grpChoiceBurgers, grpFries etc are. 

I've done this very quickly and so didn't have time to give the radiobuttons, labels and the (very small) panels used to produce square symbols sensible names but I've included the designer code so you can see what names I've actually used.

Public Class frmMenu

    Private Sub btnCompute_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles btnCompute.Click
        If Not RadioButton1.Checked AndAlso Not RadioButton2.Checked AndAlso Not RadioButton3.Checked AndAlso Not RadioButton4.Checked Then
            MessageBox.Show("You must choose a burger")
            Return
        End If
        Dim cost As Decimal = 0
        If RadioButton1.Checked Then
            cost = 4.19
        ElseIf RadioButton2.Checked OrElse RadioButton3.Checked Then
            cost = 4.79
        Else
            cost = 5.39
        End If

        If RadioButton5.Checked Then
            cost += 2.39
        ElseIf RadioButton6.Checked Then
            cost += 3.09
        ElseIf RadioButton7.Checked Then
            cost += 4.99
        End If

        If RadioButton8.Checked Then
            cost += 1.69
        ElseIf RadioButton9.Checked Then
            cost += 1.49
        End If

        txtCost.Text = cost.ToString("F2")

    End Sub

    Private Sub btnReset_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles btnReset.Click
       
        RadioButton1.Checked = False
        RadioButton2.Checked = False
        RadioButton3.Checked = False
        RadioButton4.Checked = False
        RadioButton5.Checked = False
        RadioButton6.Checked = False
        RadioButton7.Checked = False
        RadioButton8.Checked = False
        RadioButton9.Checked = False
        txtCost.Text = ""

    End Sub

End Class

' designer code

_
Partial Class frmMenu
    Inherits System.Windows.Forms.Form

    'Form overrides dispose to clean up the component list.
    _
    Protected Overrides Sub Dispose(ByVal disposing As Boolean)
        Try
            If disposing AndAlso components IsNot Nothing Then
                components.Dispose()
            End If
        Finally
            MyBase.Dispose(disposing)
        End Try
    End Sub

    'Required by the Windows Form Designer
    Private components As System.ComponentModel.IContainer

    'NOTE: The following procedure is required by the Windows Form Designer
    'It can be modified using the Windows Form Designer.  
    'Do not modify it using the code editor.
    _
    Private Sub InitializeComponent()
        Me.Panel1 = New System.Windows.Forms.Panel()
        Me.Panel2 = New System.Windows.Forms.Panel()
        Me.Panel3 = New System.Windows.Forms.Panel()
        Me.Label1 = New System.Windows.Forms.Label()
        Me.Label2 = New System.Windows.Forms.Label()
        Me.Label3 = New System.Windows.Forms.Label()
        Me.pnlBurgers = New System.Windows.Forms.Panel()
        Me.RadioButton1 = New System.Windows.Forms.RadioButton()
        Me.RadioButton2 = New System.Windows.Forms.RadioButton()
        Me.RadioButton3 = New System.Windows.Forms.RadioButton()
        Me.RadioButton4 = New System.Windows.Forms.RadioButton()
        Me.pnlFries = New System.Windows.Forms.Panel()
        Me.RadioButton5 = New System.Windows.Forms.RadioButton()
        Me.RadioButton6 = New System.Windows.Forms.RadioButton()
        Me.RadioButton7 = New System.Windows.Forms.RadioButton()
        Me.pnlDrinks = New System.Windows.Forms.Panel()
        Me.RadioButton8 = New System.Windows.Forms.RadioButton()
        Me.RadioButton9 = New System.Windows.Forms.RadioButton()
        Me.Label4 = New System.Windows.Forms.Label()
        Me.txtCost = New System.Windows.Forms.TextBox()
        Me.btnCompute = New System.Windows.Forms.Button()
        Me.btnReset = New System.Windows.Forms.Button()
        Me.Label5 = New System.Windows.Forms.Label()
        Me.Label6 = New System.Windows.Forms.Label()
        Me.Label7 = New System.Windows.Forms.Label()
        Me.pnlBurgers.SuspendLayout()
        Me.pnlFries.SuspendLayout()
        Me.pnlDrinks.SuspendLayout()
        Me.SuspendLayout()
        '
        'Panel1
        '
        Me.Panel1.BorderStyle = System.Windows.Forms.BorderStyle.Fixed3D
        Me.Panel1.Location = New System.Drawing.Point(21, 69)
        Me.Panel1.Name = "Panel1"
        Me.Panel1.Size = New System.Drawing.Size(14, 15)
        Me.Panel1.TabIndex = 0
        '
        'Panel2
        '
        Me.Panel2.BorderStyle = System.Windows.Forms.BorderStyle.Fixed3D
        Me.Panel2.Location = New System.Drawing.Point(21, 257)
        Me.Panel2.Name = "Panel2"
        Me.Panel2.Size = New System.Drawing.Size(14, 15)
        Me.Panel2.TabIndex = 1
        '
        'Panel3
        '
        Me.Panel3.BorderStyle = System.Windows.Forms.BorderStyle.Fixed3D
        Me.Panel3.Location = New System.Drawing.Point(21, 367)
        Me.Panel3.Name = "Panel3"
        Me.Panel3.Size = New System.Drawing.Size(14, 15)
        Me.Panel3.TabIndex = 2
        '
        'Label1
        '
        Me.Label1.AutoSize = True
        Me.Label1.Location = New System.Drawing.Point(55, 69)
        Me.Label1.Name = "Label1"
        Me.Label1.Size = New System.Drawing.Size(43, 13)
        Me.Label1.TabIndex = 3
        Me.Label1.Text = "Burgers"
        '
        'Label2
        '
        Me.Label2.AutoSize = True
        Me.Label2.Location = New System.Drawing.Point(63, 257)
        Me.Label2.Name = "Label2"
        Me.Label2.Size = New System.Drawing.Size(29, 13)
        Me.Label2.TabIndex = 4
        Me.Label2.Text = "Fries"
        '
        'Label3
        '
        Me.Label3.AutoSize = True
        Me.Label3.Location = New System.Drawing.Point(61, 367)
        Me.Label3.Name = "Label3"
        Me.Label3.Size = New System.Drawing.Size(37, 13)
        Me.Label3.TabIndex = 5
        Me.Label3.Text = "Drinks"
        '
        'pnlBurgers
        '
        Me.pnlBurgers.BorderStyle = System.Windows.Forms.BorderStyle.FixedSingle
        Me.pnlBurgers.Controls.Add(Me.RadioButton4)
        Me.pnlBurgers.Controls.Add(Me.RadioButton3)
        Me.pnlBurgers.Controls.Add(Me.RadioButton2)
        Me.pnlBurgers.Controls.Add(Me.RadioButton1)
        Me.pnlBurgers.Location = New System.Drawing.Point(127, 25)
        Me.pnlBurgers.Name = "pnlBurgers"
        Me.pnlBurgers.Size = New System.Drawing.Size(200, 138)
        Me.pnlBurgers.TabIndex = 6
        '
        'RadioButton1
        '
        Me.RadioButton1.AutoSize = True
        Me.RadioButton1.Location = New System.Drawing.Point(15, 19)
        Me.RadioButton1.Name = "RadioButton1"
        Me.RadioButton1.Size = New System.Drawing.Size(92, 17)
        Me.RadioButton1.TabIndex = 7
        Me.RadioButton1.TabStop = True
        Me.RadioButton1.Text = "Regular (4.19)"
        Me.RadioButton1.UseVisualStyleBackColor = True
        '
        'RadioButton2
        '
        Me.RadioButton2.AutoSize = True
        Me.RadioButton2.Location = New System.Drawing.Point(15, 44)
        Me.RadioButton2.Name = "RadioButton2"
        Me.RadioButton2.Size = New System.Drawing.Size(103, 17)
        Me.RadioButton2.TabIndex = 8
        Me.RadioButton2.TabStop = True
        Me.RadioButton2.Text = "w/cheese (4.79)"
        Me.RadioButton2.UseVisualStyleBackColor = True
        '
        'RadioButton3
        '
        Me.RadioButton3.AutoSize = True
        Me.RadioButton3.Location = New System.Drawing.Point(15, 74)
        Me.RadioButton3.Name = "RadioButton3"
        Me.RadioButton3.Size = New System.Drawing.Size(98, 17)
        Me.RadioButton3.TabIndex = 9
        Me.RadioButton3.TabStop = True
        Me.RadioButton3.Text = "w/bacon (4.79)"
        Me.RadioButton3.UseVisualStyleBackColor = True
        '
        'RadioButton4
        '
        Me.RadioButton4.AutoSize = True
        Me.RadioButton4.Location = New System.Drawing.Point(15, 103)
        Me.RadioButton4.Name = "RadioButton4"
        Me.RadioButton4.Size = New System.Drawing.Size(157, 17)
        Me.RadioButton4.TabIndex = 10
        Me.RadioButton4.TabStop = True
        Me.RadioButton4.Text = "w/bacon and cheese (5.39)"
        Me.RadioButton4.UseVisualStyleBackColor = True
        '
        'pnlFries
        '
        Me.pnlFries.BorderStyle = System.Windows.Forms.BorderStyle.FixedSingle
        Me.pnlFries.Controls.Add(Me.RadioButton7)
        Me.pnlFries.Controls.Add(Me.RadioButton6)
        Me.pnlFries.Controls.Add(Me.RadioButton5)
        Me.pnlFries.Location = New System.Drawing.Point(127, 203)
        Me.pnlFries.Name = "pnlFries"
        Me.pnlFries.Size = New System.Drawing.Size(200, 93)
        Me.pnlFries.TabIndex = 7
        '
        'RadioButton5
        '
        Me.RadioButton5.AutoSize = True
        Me.RadioButton5.Location = New System.Drawing.Point(15, 30)
        Me.RadioButton5.Name = "RadioButton5"
        Me.RadioButton5.Size = New System.Drawing.Size(80, 17)
        Me.RadioButton5.TabIndex = 0
        Me.RadioButton5.TabStop = True
        Me.RadioButton5.Text = "Small (2.39)"
        Me.RadioButton5.UseVisualStyleBackColor = True
        '
        'RadioButton6
        '
        Me.RadioButton6.AutoSize = True
        Me.RadioButton6.Location = New System.Drawing.Point(15, 53)
        Me.RadioButton6.Name = "RadioButton6"
        Me.RadioButton6.Size = New System.Drawing.Size(92, 17)
        Me.RadioButton6.TabIndex = 1
        Me.RadioButton6.TabStop = True
        Me.RadioButton6.Text = "Medium (3.09)"
        Me.RadioButton6.UseVisualStyleBackColor = True
        '
        'RadioButton7
        '
        Me.RadioButton7.AutoSize = True
        Me.RadioButton7.Location = New System.Drawing.Point(13, 93)
        Me.RadioButton7.Name = "RadioButton7"
        Me.RadioButton7.Size = New System.Drawing.Size(82, 17)
        Me.RadioButton7.TabIndex = 2
        Me.RadioButton7.TabStop = True
        Me.RadioButton7.Text = "Large (4.99)"
        Me.RadioButton7.UseVisualStyleBackColor = True
        '
        'pnlDrinks
        '
        Me.pnlDrinks.BorderStyle = System.Windows.Forms.BorderStyle.FixedSingle
        Me.pnlDrinks.Controls.Add(Me.RadioButton9)
        Me.pnlDrinks.Controls.Add(Me.RadioButton8)
        Me.pnlDrinks.Location = New System.Drawing.Point(127, 322)
        Me.pnlDrinks.Name = "pnlDrinks"
        Me.pnlDrinks.Size = New System.Drawing.Size(200, 87)
        Me.pnlDrinks.TabIndex = 8
        '
        'RadioButton8
        '
        Me.RadioButton8.AutoSize = True
        Me.RadioButton8.Location = New System.Drawing.Point(15, 21)
        Me.RadioButton8.Name = "RadioButton8"
        Me.RadioButton8.Size = New System.Drawing.Size(80, 17)
        Me.RadioButton8.TabIndex = 3
        Me.RadioButton8.TabStop = True
        Me.RadioButton8.Text = "Soda (1.69)"
        Me.RadioButton8.UseVisualStyleBackColor = True
        '
        'RadioButton9
        '
        Me.RadioButton9.AutoSize = True
        Me.RadioButton9.Location = New System.Drawing.Point(15, 47)
        Me.RadioButton9.Name = "RadioButton9"
        Me.RadioButton9.Size = New System.Drawing.Size(120, 17)
        Me.RadioButton9.TabIndex = 4
        Me.RadioButton9.TabStop = True
        Me.RadioButton9.Text = "Bottled Water (1.49)"
        Me.RadioButton9.UseVisualStyleBackColor = True
        '
        'Label4
        '
        Me.Label4.AutoSize = True
        Me.Label4.Location = New System.Drawing.Point(345, 372)
        Me.Label4.Name = "Label4"
        Me.Label4.Size = New System.Drawing.Size(74, 13)
        Me.Label4.TabIndex = 9
        Me.Label4.Text = "Cost of meal : "
        '
        'txtCost
        '
        Me.txtCost.Location = New System.Drawing.Point(438, 367)
        Me.txtCost.Name = "txtCost"
        Me.txtCost.Size = New System.Drawing.Size(100, 20)
        Me.txtCost.TabIndex = 10
        '
        'btnCompute
        '
        Me.btnCompute.Location = New System.Drawing.Point(403, 300)
        Me.btnCompute.Name = "btnCompute"
        Me.btnCompute.Size = New System.Drawing.Size(87, 40)
        Me.btnCompute.TabIndex = 11
        Me.btnCompute.Text = "Compute cost of meal"
        Me.btnCompute.UseVisualStyleBackColor = True
        '
        'btnReset
        '
        Me.btnReset.Location = New System.Drawing.Point(403, 61)
        Me.btnReset.Name = "btnReset"
        Me.btnReset.Size = New System.Drawing.Size(75, 23)
        Me.btnReset.TabIndex = 12
        Me.btnReset.Text = "Reset Form"
        Me.btnReset.UseVisualStyleBackColor = True
        '
        'Label5
        '
        Me.Label5.AutoSize = True
        Me.Label5.Location = New System.Drawing.Point(146, 19)
        Me.Label5.Name = "Label5"
        Me.Label5.Size = New System.Drawing.Size(99, 13)
        Me.Label5.TabIndex = 13
        Me.Label5.Text = "Choices for Burgers"
        '
        'Label6
        '
        Me.Label6.AutoSize = True
        Me.Label6.Location = New System.Drawing.Point(160, 198)
        Me.Label6.Name = "Label6"
        Me.Label6.Size = New System.Drawing.Size(85, 13)
        Me.Label6.TabIndex = 14
        Me.Label6.Text = "Choices for Fries"
        '
        'Label7
        '
        Me.Label7.AutoSize = True
        Me.Label7.Location = New System.Drawing.Point(160, 314)
        Me.Label7.Name = "Label7"
        Me.Label7.Size = New System.Drawing.Size(93, 13)
        Me.Label7.TabIndex = 3
        Me.Label7.Text = "Choices for Drinks"
        '
        'frmMenu
        '
        Me.AutoScaleDimensions = New System.Drawing.SizeF(6.0!, 13.0!)
        Me.AutoScaleMode = System.Windows.Forms.AutoScaleMode.Font
        Me.ClientSize = New System.Drawing.Size(550, 448)
        Me.Controls.Add(Me.Label7)
        Me.Controls.Add(Me.Label6)
        Me.Controls.Add(Me.Label5)
        Me.Controls.Add(Me.btnReset)
        Me.Controls.Add(Me.btnCompute)
        Me.Controls.Add(Me.txtCost)
        Me.Controls.Add(Me.Label4)
        Me.Controls.Add(Me.pnlDrinks)
        Me.Controls.Add(Me.pnlFries)
        Me.Controls.Add(Me.pnlBurgers)
        Me.Controls.Add(Me.Label3)
        Me.Controls.Add(Me.Label2)
        Me.Controls.Add(Me.Label1)
        Me.Controls.Add(Me.Panel3)
        Me.Controls.Add(Me.Panel2)
        Me.Controls.Add(Me.Panel1)
        Me.Name = "frmMenu"
        Me.Text = "Menu"
        Me.pnlBurgers.ResumeLayout(False)
        Me.pnlBurgers.PerformLayout()
        Me.pnlFries.ResumeLayout(False)
        Me.pnlFries.PerformLayout()
        Me.pnlDrinks.ResumeLayout(False)
        Me.pnlDrinks.PerformLayout()
        Me.ResumeLayout(False)
        Me.PerformLayout()

    End Sub
    Friend WithEvents Panel1 As System.Windows.Forms.Panel
    Friend WithEvents Panel2 As System.Windows.Forms.Panel
    Friend WithEvents Panel3 As System.Windows.Forms.Panel
    Friend WithEvents Label1 As System.Windows.Forms.Label
    Friend WithEvents Label2 As System.Windows.Forms.Label
    Friend WithEvents Label3 As System.Windows.Forms.Label
    Friend WithEvents pnlBurgers As System.Windows.Forms.Panel
    Friend WithEvents RadioButton4 As System.Windows.Forms.RadioButton
    Friend WithEvents RadioButton3 As System.Windows.Forms.RadioButton
    Friend WithEvents RadioButton2 As System.Windows.Forms.RadioButton
    Friend WithEvents RadioButton1 As System.Windows.Forms.RadioButton
    Friend WithEvents pnlFries As System.Windows.Forms.Panel
    Friend WithEvents RadioButton7 As System.Windows.Forms.RadioButton
    Friend WithEvents RadioButton6 As System.Windows.Forms.RadioButton
    Friend WithEvents RadioButton5 As System.Windows.Forms.RadioButton
    Friend WithEvents pnlDrinks As System.Windows.Forms.Panel
    Friend WithEvents Label7 As System.Windows.Forms.Label
    Friend WithEvents RadioButton9 As System.Windows.Forms.RadioButton
    Friend WithEvents RadioButton8 As System.Windows.Forms.RadioButton
    Friend WithEvents Label4 As System.Windows.Forms.Label
    Friend WithEvents txtCost As System.Windows.Forms.TextBox
    Friend WithEvents btnCompute As System.Windows.Forms.Button
    Friend WithEvents btnReset As System.Windows.Forms.Button
    Friend WithEvents Label5 As System.Windows.Forms.Label
    Friend WithEvents Label6 As System.Windows.Forms.Label

End Class