Is it good to work on MVVM , MVP and MPF?

I think both MVP and MVVM offers better modular structure than MVC. If you want to build simple applications then even MVC would work fine.

But, anything more complex which requires frequent updates, you should focus on MVVM.

In short, it really depends on the use-case and what do you want to build.

Here are some use-cases that I can think of:

Does your app has the potential to scale in the future? Simply, focus on MVM or MVVM.

Are you working on a project where there is a heavy scope for reusable components. Choose MVVM.

If you’re working in a large where collaboration and continuous integration is important. Choose MVVM.

If you want to combine two or more activities in a single screen. Like payment form and confirmation. Choose MVP.